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Wellbutrin vs. Generic Bupropion

Are there differences between the antidepressant Wellbutrin and generic bupropion? See ConsumerLab.com's independent tests of these drugs, get tips for getting the right drug, and more. If you or a loved one uses generic Wellbutrin, you need to know how products may differ.

Wellbutrin vs. Generic Bupropion Review

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Clinical Update

12/09/2012

Failure of Generic Antidepressant Drug

In October, the FDA withdrew its approval of a generic version of the popular antidepressant drug, Wellbutrin XL. This came 5 years after ConsumerLab.com first reported a potential problem with the drug. This week, more disturbing details emerged about this generic drug and why it was originally approved by the FDA. For more about this, see the Update in the report Wellbutrin vs. Generic Bupropion. More >>

Clinical Update

1/17/2023

Antidepressants and Tinnitus?

Find out if the antidepressant bupropion (Wellbutrin) can cause ringing in the ears (tinnitus), and see a list of other medications that may have this effect in our article about tinnitus.

Clinical Update

10/17/2013

FDA Finds Another Generic Drug Not Equivalent

According to the FDA, a marketed generic version of the antidepressant buproprion hydrochloride XL (300 mg) is not equivalent to the brand name Wellbutrin XL and the product is being removed from the market. One year ago, another generic version of this drug was removed from the market for the same reason. ConsumerLab.com first reported potential problems with these products in 2007 but the FDA was slow to take action. For details, see the updated in the Wellbutrin vs Generic Budeprion Review >>

News Release

October 04, 2012

Five Years After ConsumerLab.com Reported a Problem, FDA Agrees Generic Version of Wellbutrin XL Is Not Equivalent and Is Pulled Off Market — Important Lessons about Generics

White Plains, New York — October 4, 2012 [Updated 10/11/12]— Are all generic drugs therapeutically equivalent to their brand name counterparts? Until yesterday, the FDA, and many others, adamantly said they were.

News Release

April 16, 2008

FDA's investigation of generic antidepresssant called inadequate by ConsumerLab.com and The People's Pharmacy

WHITE PLAINS, NEW YORK AND DURHAM, NORTH CAROLINA — APRIL 16, 2008 — After waiting more than six months for results of the FDA's investigation of a generic version of Wellbutrin XL 300 (Budeprion XL 300), ConsumerLab.

News Release

March 17, 2008

As problems surface, Consumerlab.com and the people's pharmacy ask FDA to disclose differences between generic and original drugs

WHITE PLAINS, NEW YORK AND DURHAM, NORTH CAROLINA — MARCH 17, 2008 — An investigation by ConsumerLab.

CL Answer

Will pregnenolone help slow down aging or reduce chronic pain?

Learn more about the steroid hormone pregnenolone, including its effects in the body and on aging and chronic pain.

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CL Answer

Does cat’s claw have any health benefits and is it safe?

Cat's claw is promoted for numerous conditions, including arthritis (including osteoarthritis and rheumatoid arthritis), Alzheimer's disease, viral infections, boosting immune response to vaccination, and reducing side effects of chemotherapy. Find out if it works and if it's safe.

Cats claw extract capsules in a bowl on a table

News Release

October 12, 2007

ConsumerLab.com finds generic antidepressant behaves differently from original drug. May explain complaints by patients. — Generic drug equality questioned

WHITE PLAINS, NEW YORK AND DURHAM, NORTH CARLOLINA — OCTOBER 12, 2007 — ConsumerLab.

Clinical Update

10/07/2024

Turmeric Supplements vs Spices

How do turmeric supplements compare to turmeric spices in terms of potentially beneficial curcumin compounds and contamination with toxic heavy metals? Find out in our article about turmeric supplements vs. spices. Also see our Top Picks among turmeric supplements and spices.

Clinical Update

12/05/2024

Remineralizing Tooth Powder?

Is Remineralizing Tooth Powder by Living well With Dr. Michelle better than a toothpaste? Find out what research suggests in the Toothpaste vs. tooth powder vs. toothpaste tablets section of our article about finding the best toothpaste, which includes our Top Picks for cavity prevention, desensitization, bleeding gums, whitening surface stains, dry mouth, and bad breath.

Clinical Update

6/17/2020

Whey vs. Casein vs. Neither

A study among elderly men engaged in strength training compared the effects of supplementing with whey protein, casein protein, or neither. Learn what the study showed in the What It Does section of the Protein Powders Review. Also see our Top Picks among protein powders.

Recalls & Warnings

December 07, 2014

FDA Raises Concerns Over Generic ADHD Drugs

On November 13, 2014, the U.S.

Recalls & Warnings

October 02, 2008

FDA Permits Incorrect Labeling on Generic Wellbutrin XL, But May Require Drug to be Tested

The FDA has acknowledged inconsistencies in the labeling of Budeprion XL, a generic version of the antidepressant Wellbutrin XL, according to an October 2, 2008 article from Dow Jones News service.