Reviews and Information for Saffron
Saffron Supplements
Supplements made with saffron extracts have been the focus of many small clinical studies for depression and anxiety, sleep, and cognition. But are they effective, and which saffron supplements deliver the right dose and best quality? See what ConsumerLab's independent testing and review revealed.
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News Release
February 13, 2023
Saffron Supplements Vary Widely in Key Compounds, According to ConsumerLab Tests
White Plains, New York, February 13, 2023 — Saffron extracts are promoted to treat mood, improve cognition and vision, and even reduce appetite.
Product Review
Vision Supplements Review (with Lutein, Zeaxanthin & AREDS2 Formulas)
Find the Best Vision Supplement Based Our Tests

Clinical Update
4/09/2024
Fake Saffron
Recent tests of saffron supplements by researchers at a U.S. university found most products contained "no saffron compounds." For details and to see what ConsumerLab found in its own tests, see our Saffron Supplements Review, which includes our two Top Picks for saffron.
Clinical Update
11/20/2024
Saffron Top Picks
Unfortunately, our original Top Picks among saffron supplements have been discontinued. See our recommended alternatives in the Saffron Supplements Review.
Clinical Update
4/09/2024
Saffron for Fatty Liver?
Did taking a saffron supplement decrease liver fat in people with fatty liver disease? Find out what a recent study showed in our Saffron Supplements Review. Also see our Top Picks among saffron supplements.
Clinical Update
7/07/2023
Saffron for Stress?
Can saffron reduce stress and anxiety? See what a recent study found in the What It Does section of our Saffron Supplements Review, which includes our Top Picks among saffron supplements.
Also see: Do any supplements help relieve stress?
CL Answer
What are the best supplements for depression and anxiety?
Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.

Recalls & Warnings
December 12, 2022
FDA Warns Saffron USA for Promoting Teas to Treat Insomnia, Osteoporosis & Cancer
On September 23, 2022, the FDA issued a warning letter to Saffron USA LLC following inspection of the company’s website which found statements about its Allergy Blend, Chamomile Tea Petals, Diabetic Support Blend, Orange Blast Tea, and Saffron Loose Tea products to be drug ...
Clinical Update
5/24/2022
Saffron and Blood Thinners
Saffron may interact with blood-thinning medications such as rivaroxaban (Xarelto), according to a recent report. Get the details in our updated answer to the question: Are there supplements I should avoid when taking apixaban (Eliquis) or similar blood thinner drugs like Xarelto?
Clinical Update
2/18/2020
Saffron for Better Sleep?
A recent, preliminary study suggests that saffron may help with sleep. Get the details plus information about other supplements that may help or interfere with sleep, in our answer to the question: Which supplements can help me sleep?
Clinical Update
4/30/2019
Saffron for Vision
Saffron, which contains carotenoids, may improve visual acuity in people with age-related macular degeneration (AMD) according to a recent study. For details, see the ConsumerTips section of the Vision Supplements Review. Also see which vision supplements most closely resemble the ideal formula to slow the progression of AMD.
Clinical Update
2/07/2021
Saffron for Mood?
Does saffron extract improve mood in people feeling down and anxious or stressed? See what a new study found in our article about Supplements for Depression and Anxiety.
Clinical Update
5/01/2021
Saffron for Sleep?
Can saffron extract improve sleep in people with mild to moderate insomnia? See what a new study found in our updated answer to the question: Which supplements can help me sleep and which cause insomnia?
Clinical Update
9/04/2021
Saffron for Better Sleep?
Can taking saffron extract improve sleep in people with insomnia? See what a recent study found in our updated article about Supplements and Sleep.
CL Answer
I take warfarin (Coumadin), an anticoagulant drug. Are there supplements I should avoid, or be taking, due to this drug?
Find out which supplements should be avoided when taking blood thinners (anticoagulants) like warfarin (Coumadin), including vitamin K, St. John's wort, and curcumin.

Recalls & Warnings
December 01, 2021
FDA Warns Seller of Saffron Supplements
On November 18th, 2021, the FDA issued a warning letter to Saffron Health Sciences following a review of the company's website, social media, and Amazon product listings, which found statements made about the company's products Crocin Rich, Crocin Rich II, and Crocin Rich ...
CL Answer
What supplements should I stop taking before surgery?
Info on which supplements to avoid before surgery due to increased risk of bleeding or interference with anesthesia.

CL Answer
Do any supplements help relieve stress?
Are there actually supplements for stress relief and panic attacks? Learn more about holy basil, fish oil, L-theanine, and ginseng.

CL Answer
Are there supplements I should avoid when taking apixaban (Eliquis) or similar blood thinner drugs like Xarelto?
Learn about supplement interactions with apixaban (Eliquis), rivaroxaban (Xarelto) and other blood thinner drugs in the direct factor Xa inhibitors class.

CL Answer
Which supplements and lifestyle changes improve sleep, and which cause insomnia?
Find out which vitamins may help you sleep and learn if any vitamins or supplements can cause insomnia.

CL Answer
Which supplements help reduce the risk of colorectal cancer?
Find out which supplements may reduce the risk of colorectal cancer, including folate, fiber, selenium, and vitamin D.

Recalls & Warnings
May 04, 2023
FDA Warns MedoLife for Promoting Homeopathic Products to Treat COVID-19, Cancer
On April 19, 2023, the FDA issued a warning letter to Medolife Rx D/B/A MedoLife Corp., AELIA Inc. and Queanta Inc.
Recalls & Warnings
May 24, 2023
Seller of Echinacea, High Blood Pressure Products & More Warned for Drug Claims
On May 12, 2023, the FDA issued a warning letter to H.E.A.L.
Recalls & Warnings
November 09, 2023
FDA Warns Biorica International for Cholesterol, Kidney & Cancer Claims
On August 4, 2023, the FDA issued a Warning Letter to Biorica International Corp. following review of the company’s websites and social media, which found statements about the company’s Plaquex Oral Supplements to be drug claims, which are not permitted for dietary supplements.
Recalls & Warnings
December 29, 2022
EarthLab, Inc. Warned for Promoting Curcumin, Elderberry to Treat Pain & Flu
On November 10, 2022, the FDA issued a warning letter to EarthLab, Inc., dba Wise Woman Herbals following inspection of the company’s website which found statements about the company’s products to be drug claims because they suggest the products can prevent or treat disease.
Recalls & Warnings
March 01, 2023
Seller of Dr. Miller’s Herbal “Detox” Teas Warned by FDA for Drug Claims
On February 3, 2023, the FDA issued a warning letter to Jackson Health & Wellness Clinic after inspection of the company’s website found statements about the company’s Dr. Miller’s Holy Tea, Dr. Miller’s Super Holy Tea, Dr. Miller’s Ultimate Tea, Dr.
Recalls & Warnings
August 16, 2023
FDA Warns Hekma Center, LLC for Promoting Products to Treat Anemia, Diabetes, Depression, & More
On June 2, 2023, the FDA issued a warning letter to Hekma Center, LLC following review of the company’s website and social media, which found statements about the company’s Natural Supplements for Anemia, Lymf (Galium aparine), Natural Supplements for Cardiomyopathy, Magic1 (Moringa ...
CL Answer
Do any supplements help with COVID-19? Do supplements like vitamin D, zinc, vitamin C, or herbals work?
Find out if natural remedies & supplements for coronavirus such as zinc, vitamin C, garlic, or elderberry help to prevent or treat COVID-19.

Recalls & Warnings
March 09, 2022
FDA Warns Seller of Magnesium, CBD, Herbal Extracts & More
On February 9, 2022, the FDA issued a warning letter to Bea Lydecker’s Naturals, Inc.
Recalls & Warnings
December 22, 2021
FDA Warns Seller of Liquid Magnesium, B-12, Berberine & More
On December 9, 2021, the FDA issued a warning letter to Wholly Liquid Nutritional Supplements LLC because it found statements on the company's website and social media about its products, including SpiroLaze, BioLaze, LiquiLaurin, VIT-B12, DeStress, and Omega Plus, to be ...