On April 17, 2007 the Food and Drug Administration (FDA) website posted an announcement that Jen-On Herbal Science International, Inc. is conducting a voluntary nationwide recall of the company's supplement product sold under the name H S Joy of Love. Jen-On Herbal Science International, Inc. is conducting this recall after being informed by representatives of the FDA that lab analysis by FDA of H S Joy of Love samples found the product contains Piperadino Vardenafil, an analog of Vardenafil, an FDA-approved drug used as treatment for male Erectile Dysfunction (ED). Piperadino Vardenafil is close in structure to Vardenafil and is expected to possess a similar pharmacological and adverse event profile. This poses a threat to consumers because the analogue may interact with nitrates found in some prescription drugs (such as nitroglycerin) and may lower blood pressure to dangerous levels. Consumers with diabetes, high blood pressure, high cholesterol, or heart disease often take nitrates. ED is a common problem in men with these conditions, and consumers may seek these types of products to enhance sexual performance.