Reviews and Information for Lithium (Low-dose)
Low-Dose Lithium Supplements
Find the best quality low-dose lithium supplement and get quality and cost comparisons for popular brands, including lithium orotate and lithium aspartate. Learn whether low-dose lithium can help for mood and memory, plus information about dosage, safety, side effects, potential drug interactions and more.
Low-Dose Lithium Supplements ReviewSearch term may appear only in full report available to members. Join now for full access.
CL Answer
Are lithium orotate supplements as effective and safe as prescription lithium for bipolar disease and depression?
Lithium orotate supplement info, including proper dosage, safety, and how lithium orotate supplements compare to prescription lithium for bipolar disease and depression.

News Release
February 01, 2024
Best Melatonin Supplements for Sleep? ConsumerLab Selects Its Top Picks
White Plains, New York, February 1, 2024 — Melatonin supplements can help you fall asleep faster, but with so many different products on the market, which provide the best quality and value? To find out, ConsumerLab recently tested 20 popular melatonin supplements, including capsules, tablets, ...
News Release
August 23, 2017
ConsumerLab.com Tests Reveal Best Low-Dose Lithium Supplements for "Mood"
White Plains, New York, August 23, 2017 — As a prescription medication, the mineral lithium is used to treat bipolar disease and other mood disorders, but some may be surprised to learn that lithium is also sold as a dietary supplement — although in much lower doses than provided by ...
Clinical Update
8/27/2017
Does Lithium Prevent Dementia?
A new study found the risk of developing dementia to be significantly lower in areas with higher levels of lithium in the drinking water. This finding is consistent with a study that found low-dose lithium to stabilize patients with Alzheimer's disease. Details about these studies are in the "What It Does" section of the Low-Dose Supplements Review, which includes our Top Picks among low-dose lithium supplements.
Clinical Update
5/26/2018
Do We Really Need More Lithium?
Studies have shown higher rates of mental illness and dementia in areas with the lowest levels of lithium in the water, suggesting that people supplement with lithium. However, a new study raises doubts about this. For details, see the What It Does section of the Low-Dose Lithium Supplements Review.
Clinical Update
10/02/2024
Low-dose Lithium for Long COVID?
Did taking low-dose lithium improve symptoms of long COVID? Find out what a recent study showed in the What It Does section of our Low-Dose Lithium Review, which includes our Top Picks for low-dose lithium.
Clinical Update
9/02/2022
Lithium for Dementia?
Does low-dose lithium stabilize or improve cognitive function in people with Alzheimer’s or other forms of cognitive decline? Find out in the What It Does section of our Low-Dose Lithium Supplements Review.
Also see our CL Answer about supplements for brain function.
Product Review
Multivitamin and Multimineral Supplements Review
Best Multivitamins -- Caution with Gummies

CL Answer
How Should You Take Care of Yourself After You’ve Had COVID-19?
Find out the best way to care for yourself when recovering from COVID-19, including how long you should quarantine, whether you should get vaccinated, when it is safe to undergo a surgery, and how to spot and, possibly, improve lingering symptoms.

CL Answer
Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?
Find out which supplements help improve memory, brain function and cognition, including fish oil, some B vitamins, cocoa, and curcumin. ConsumerLab's answer explains the evidence for supplements promoted to help with brain function and cognition.

CL Answer
I take levothyroxine (Synthroid), a thyroid hormone to treat hypothyroidism. Are there supplements or foods I should avoid, or be taking, due to this drug?
Is taking certain supplements and hypothyroidism medications bad? Learn which supplements can interact with thyroid hormone medications like levothyroxine (Synthroid), thyroid hormone levels, and laboratory tests.

Recalls & Warnings
January 10, 2018
Lithium Supplement Contaminated With E. Coli, Health Canada Warns
On December 1, 2018, Health Canada (the Canadian equivalent of the FDA) warned consumers that it found Smart Brain Formulations Serotonin Support, a lithium ororate supplement sold on the website Robert Lamberton Consulting, to be contaminated with E. choli (Escherichia coli).
CL Answer
What are "broad-spectrum micronutrient" supplements, and do they have greater health benefits than multivitamin/multimineral supplements?
Learn about "broad-spectrum micronutrients" and how they compare to multivitamin/multimineral supplements.

Recalls & Warnings
April 29, 2014
Seller of B Vitamins, CoQ10, Amino Acids and Other Supplements Warned for Manufacturing Violations and Drug Claims
On April 1, 2014, the FDA issued a warning letter to Bio-Recovery, Inc.
Recalls & Warnings
April 03, 2024
FDA Warns Ambaya Gold for Promoting Products for Depression, Cancer, & Arthritis
On December 5, 2023, the FDA issued a Warning Letter to Ambaya Gold Health Products, LLC following review of the company’s website and social media, which found statements about the company’s Brain Balance, Immune System Boost, Dentist In A Bottle, Essensiac, Fulvic Green, Silver ...
CL Answer
I read that turmeric may be a GI irritant. I have GI problems and wonder if I should avoid turmeric and curcumin?
Find out if turmeric/curcumin supplements can cause gastrointestinal irritability.

CL Answer
What is inositol hexaphosphate (IP6) and myo-inositol? Are they helpful in treating cancer or other conditions?
Inositol hexaphosphate (IP6): Find out if IP6 (also known as phytic acid) can prevent or treat cancer. Clinical evidence, dosage, safety and how IP6 differs from myo-inositol. Consumerlab.com's answer explains.

CL Answer
I have low blood pressure. Are there any supplements I should avoid?
Find out which supplements can cause decreases in blood pressure, including melatonin, arginine, magnesium, and calcium.

CL Answer
Which supplements help reduce the risk of colorectal cancer?
Find out which supplements may reduce the risk of colorectal cancer, including folate, fiber, selenium, and vitamin D.

CL Answer
I take warfarin (Coumadin), an anticoagulant drug. Are there supplements I should avoid, or be taking, due to this drug?
Find out which supplements should be avoided when taking blood thinners (anticoagulants) like warfarin (Coumadin), including vitamin K, St. John's wort, and curcumin.

CL Answer
Which supplements can help treat anemia? Do any supplements cause a low red blood cell count?
Find out which vitamin and nutrient supplements can help prevent and treat anemia in people who are nutrient deficient and learn which supplements may cause low blood cell counts, especially when used in excess.

CL Answer
As vitamin D is a fat-soluble vitamin, why is it necessary to take it every day?
Find out how best to take vitamin D supplements, including cautions on overdoses.

CL Answer
Are fruit and vegetable “washes” or devices more effective than water for cleaning produce and removing pesticides? Are they safe?
Fruit and veggie washes, vinegar, and baking soda, as well as devices that use electrolysis, ozone water, or ultrasonic cleaning, are often promoted for removing dirt, bacteria and pesticides from produce. Find out if any work better than rinsing with water and if they are safe.

Recalls & Warnings
August 09, 2012
Makers of Mineral Water Containing Lithium Warned
On July 20, 2012, the FDA issued a warning letter to Lithia Mineral Water, Inc. declaring Lithia mineral water product to be an approved drug following a 2011 facility inspection.
Clinical Update
9/16/2022
A Caution with Low-dose Minoxidil
Although rare, be aware that serious side effects due to pharmacy errors have been reported with low-dose oral minoxidil preparations. Get the details in the How to get low-dose oral minoxidil section of our CL Answer about supplements for hair.
Clinical Update
10/14/2022
Side Effect of Low-Dose Oral Minoxidil
A case of severe fluid buildup was recently reported in a woman taking low-dose minoxidil. Get the details, and learn what some doctors now recommend when starting low-dose oral minoxidil treatment in our article about hair treatments.
Recalls & Warnings
November 02, 2012
Manufacturer of Prostate, Inflammation and Cholesterol Supplements Warned For Drug Claims
On October 15, 2012, the FDA issued a warning letter to Ortho Molecular Products, Inc. for making drug claims about the following dietary supplements: Candicid Forte, Inflamma-bLOX, Lipitrol, Mucosagen, Prostatrol Forte, Resvoxitrol, Paracid Forte, VascuPak HTN and Lithium Orotate.
Clinical Update
11/02/2021
Low-Dose Prednisone and COVID Vaccines
Find out if taking low-dose prednisone reduces immune response to the COVID-19 vaccine.
Clinical Update
6/17/2015
High-Dose Vitamin D Increases Upper Respiratory Infections
A study among older people found that taking a high dose of vitamin D every 2 months increased the risk of upper respiratory infection by 48% compared to taking low-dose vitamin D daily. Infections lasted two days longer for those taking the high dose versus the low dose. For details, including dosage, as well as our test reports on vitamin D supplements, see the Vitamin D Supplements Review >>
Clinical Update
Clinical Update
10/31/2020
Warfarin and Low-Dose Vitamin K
Should people on warfarin (Coumadin) take low-dose vitamin K to help stabilize fluctuations in INR? Learn what experts say in the What It Does section of our Vitamin K Supplements Review. Also, learn if other blood thinning drugs are affected by vitamin K in the Concerns and Cautions section of our review.
Clinical Update
1/15/2019
Anxiety Treatment -- Low-Dose CBD?
Does low-dose CBD (cannabidiol) help with anxiety and sleep disorders? See the results of a recently published case series in the What It Does section of the CBD & Hemp Extract Supplements Review. Also see our Top Pick for CBD.
Clinical Update
10/02/2021
Low-Dose Red Yeast Rice for Cholesterol?
Can a low dose of red yeast rice significantly lower cholesterol levels? See what a recent clinical study found in the What It Does section of our Red Yeast Rice Supplements Review. Also see our Top Pick among red yeast rice supplements.
Clinical Update
10/06/2013
Vitamin D for Post-Menopausal Women
A study compared the effects of low-dose and high-dose vitamin D on bone mineral density in post-menopausal women who were also supplemented with calcium. Both dosages helped prevent loss of bone mineral density, but the higher dose was less efficient in reducing bone turnover, i.e., bone loss, contrary to what the researchers expected. For details, including dosage, see the updated Vitamin D Supplements Review>>
Clinical Update
8/30/2022
Getting Minoxidil for Hair
A CL Member asked how to get low-dose minoxidil (for hair growth), since it usually comes in higher-dose tablets. Find out in our article about supplements and treatments for hair.
Clinical Update
6/20/2023
Zinc Caution
Taking very high doses of zinc, even short-term, can cause dangerously low blood sugar in people with no previous history of low blood sugar, as recently highlighted in a series of reports. Get the details in the Concerns and Cautions section of our Zinc Supplements and Lozenges Review, which includes our Top Picks among zinc products.
Clinical Update
6/27/2023
Aspirin & Anemia Risk
Taking daily, low-dose aspirin may increase the risk of iron-deficiency anemia in older men and women, according to a recent study. Get the details in our Iron Supplements Review.
Also see our Top Picks among iron supplements.
Clinical Update
4/12/2024
Oral vs. Topical Minoxidil
How does taking low-dose minoxidil as a pill compare with topical minoxidil for hair growth? See what a recent study found in our article about supplements and treatments for hair.
Clinical Update
12/09/2024
Caution With Vitamin D Drops
Liquid vitamin D drops are often given to infants, but it’s critical to use a low-dose product to avoid toxicity, as occurred in a recently reported case. For details, see the Concerns and Cautions section of our Vitamin D Supplements Review.
Clinical Update
3/29/2022
Collagen for Joint Discomfort?
Can supplementing with low-dose collagen reduce joint pain in healthy older adults? Find out what a recent study showed in the Joint Pain section of our Collagen Supplements Review. Also see our Top Picks for collagen.
Clinical Update
8/26/2022
Hair Growth Compared
We received and answered the following questions this week:
Clinical Update
11/11/2022
Aspirin Causing Falls
Taking low-dose aspirin increased the risk of serious falls in a recent study. Get the details in our article: Do any supplements improve balance or reduce the risk of falls?
Clinical Update
11/15/2022
Statin vs. Supplements for Lowering Cholesterol
A low-dose statin drug was much more effective than 5 different supplements at lowering cholesterol in a recent study. However, 3 of the supplements had previously failed ConsumerLab reviews, another was the wrong form, and the fifth may not have been used properly, likely skewing the findings. Top Picks from our Reviews, used properly, would have likely yielded better results. For details, see our article about supplements to lower cholesterol.
Clinical Update
1/19/2014
Multivitamin Lowers Cataract Risk
A large, long-term study using a low-dose multivitamin found that it reduced the risk of developing cataract (a clouding of the lens of the eye) by 9% compared to placebo. Interestingly, the reduced risk of cataract was negated when a separate vitamin C supplement was also taken. For details about the study and dosage, as well as our tests and comparison of multivitamins, see the updated Multivitamin and Multimineral Supplements Review.
Clinical Update
4/28/2017
Vitamin D for Muscle and Balance?
Why did a recent study show that both high and low-dose vitamin D didn't improve muscle strength or balance in women despite the fact that other studies have shown vitamin D to help? The likely answer has to do with the vitamin D status (i.e., blood levels) of the people chosen to participate in these studies. To find out what you should do to improve your balance and reduce your chance of falling, see the "Muscle, Balance and Falls" section of the Vitamin D Supplements Review >>
Clinical Update
7/16/2014
DHA for Periodontitis (Inflammation Around Teeth)
A new study found that giving DHA (from algal oil) along with low-dose aspirin led to greater reductions in local inflammation and pocketing around teeth than aspirin plus placebo. For more about the study, including dosage, and our tests and comparisons of algal oil supplements, see the Fish Oil and Omega-3 Fatty Acid Supplements Review (Including Krill, Algae, Calamari, Green-lipped Mussel Oil) >>
Clinical Update
3/08/2019
CBD & Cancer
Preliminary evidence suggests that CBD (cannabidiol) may have anti-cancer properties, and a dramatic reduction in tumor size was recently reported in a person taking low-dose CBD. For details, see the What It Does section of the CBD Oils and Hemp Extracts Review.
Clinical Update
6/20/2018
Melatonin for Poor Sleepers
For people who cannot fall asleep until early morning, a recent study showed some benefit with a low-dose form of melatonin. For details, see the What It Does section of the Melatonin Supplements Review. (Also see our Top Picks among melatonin supplements.)
Clinical Update
6/15/2021
Vitamin D May Increase the Risk of Fractures from Falls
Taking doses of vitamin D above the RDA when not necessary may increase the risk of first-time falls with fractures, according to a recent analysis. Get the details in the Muscle, Balance and Falls section of the Vitamin D Supplements Review. Also see our Top Picks for low, moderate and high-dose vitamin D supplements.
Clinical Update
2/25/2020
Vitamin D for Mom Affects Baby's Bones
Taking high-dose versus very-low-dose vitamin D during pregnancy led to greater bone density in offspring, according to a recent study. But, there are important caveats. Get the details in the What It Does section of the Vitamin D Supplements Review. Also see our Top Picks for vitamin D.
Clinical Update
5/20/2012
B Vitamin May Lower Blood Pressure
According to a new study, approximately 10% of the population is genetically prone to high blood pressure which may respond dramatically to a low dose of riboflavin (vitamin B-2). Read the update to the B Vitamin Supplements Review for details, including the dose used and amount of blood pressure reduction achieved. More >>
Clinical Update
3/31/2013
Low Dose of Vitamin K Helps Bone
Using a much lower dose of vitamin K than in previous studies, a new study found that intake of a particular form of vitamin K decreased age-related decline in bone mineral content and density in certain bones in postmenopausal women. Get the details, as well as our ratings of these supplements, in the updated Vitamin K Supplements Review >>
Clinical Update
10/06/2013
Vitamin D for Adolescents
A study found that vitamin D supplementation increased bone density in the hips of adolescent girls, but not of boys. Interestingly, a high dose appeared to have less effect than a low dose. For details, including dosage and our tests of vitamin D supplements, see the updated Vitamin D Supplements Review>>
Recalls & Warnings
May 23, 2015
Seller of Magnesium, Calcium, Silver and More Warned for Manufacturing Violations, Drug Claims
On May 8, 2015, the FDA issued a warning letter to Pick and Pay, Inc.
Recalls & Warnings
July 24, 2018
Contaminated Homeopathic Products Recalled
On July 20, 2018, King Bio issued a recall of four lots of its homeopathic products Aquaflora Candida HP9, Lymph Detox, and Baby Teething liquids because they were found to contain microbial contaminants including Pseudomonas Brenneri, Pseudomonas Fluroescens and ...
Recalls & Warnings
April 24, 2018
Traditional Medicinals "Throat Coat" Lemon Echinacea Herbal Tea Recalled in Canada
On April 24, 2018, Health Canada (the Canadian equivalent of the FDA) advised consumers that one lot of Traditional Medicinals Throat Coat Lemon Echinacea herbal tea is being recalled in Canada because it has the potential to contaminated by Salmonella.
Recalls & Warnings
May 17, 2013
Hoodia, Sexual Enhancement Supplements and More Found To Be Adulterated, Misbranded
On March 01, 2013, the FDA issued a warning letter to Desert Rose Manufacturing, Inc.
Recalls & Warnings
May 14, 2014
Maker of Mood, Smoking Cessation Supplements and More Warned for Violations, Drug Claims
On April 17, 2014, the FDA issued a warning letter to CDJ Holding, Incorporated, d.b.a.