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GABA Supplements

Do GABA supplements help with stress, sleep or memory, and are some GABA supplements better than others? ConsumerLab tested and reviewed popular GABA supplements, including those made with Pharma GABA, and reviewed the clinical evidence. The findings are in this report.

GABA Supplements Review

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News Release

January 23, 2025

ConsumerLab Tests Identify Best Black Currant, Borage, Evening Primrose Flax and Hemp Oils

White Plains, NY, January 23, 2025 —  Black currant, borage, evening primrose, flax, and hemp oils contain omega-3, -6, and/or -9 fatty acids that, when replacing saturated fats in the diet, may help reduce cardiovascular risk.

News Release

January 09, 2025

Not All Black Seed Oil Supplements Contain What They Claim, According to ConsumerLab

White Plains, NY, January 9, 2025 —  Black seed oil and extract supplements are promoted for controlling blood pressure, cholesterol, blood sugar, and arthritis pain, and more.

Clinical Update

5/16/2023

Solgar GABA Approved

Solgar GABA 500 mg was recently tested and Approved through our voluntary Quality Certification Program and was added to our GABA Supplements Review.

CL Answer

Which supplements may benefit people with essential tremor, and which should be avoided?

Learn about supplements used for treating essential tremor, including caprylic acid (also called octanoic acid), thiamin (vitamin B1), cannabidiol (CBD), GABA (gamma-aminobutyric acid), and branched-chain amino acids. Find out which work and which don't. Also find out which supplements and food may make essential tremors worse.

Man with essential tremor holding a cup with his right hand and bracing his wrist with his left hand

Clinical Update

5/14/2024

GABA for Sleep or Mood?

The authors of a recent study suggested that taking GABA before bedtime enhanced sleep efficiency, but we question whether it really helped at all, as discussed in the Insomnia section of our GABA Supplements Review, which includes our Top Picks among GABA supplements.

Also see: Which supplements and lifestyle changes improve sleep, and which cause insomnia?

CL Answer

Do any supplements help with COVID-19? Do supplements like vitamin D, zinc, vitamin C, or herbals work?

Find out if natural remedies & supplements for coronavirus such as zinc, vitamin C, garlic, or elderberry help to prevent or treat COVID-19.

Supplements for Coronavirus (COVID-19)? -- mask and pills

CL Answer

I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?

Learn about Prozac (fluoxetine) drug interactions along with other supplements and SSRIs.

Woman Taking Pill with Glass of Water

Clinical Update

5/05/2023

Restless Leg Syndrome: GABA vs Gabapentin

One of these can help with restless leg syndrome, while the other doesn’t. Learn the difference in our GABA Supplements Review, which includes our Top Picks for GABA.

Also see our article about supplements for restless legs syndrome.

Clinical Update

5/04/2021

GABA for Cognition?

Can taking GABA improve cognition? See what a new study found in our updated article about GABA (gamma-aminobutyric acid).

Clinical Update

12/16/2022

GABA with Antidepressants?

Can GABA (gamma-aminobutyric acid) supplements interact with antidepressant medications such as SSRIs? Find out in our updated CL Answer about possible benefits and safety of GABA.

Also see our CL Answer about supplements that may interact with SSRIs.

CL Answer

Do any supplements help with restless legs syndrome?

Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS). ConsumerLab.com's answer explains.

Supplements for Restless Legs Syndrome

CL Answer

Which supplements and lifestyle changes improve sleep, and which cause insomnia?

Find out which vitamins may help you sleep and learn if any vitamins or supplements can cause insomnia.

Clinical Update

8/05/2022

GABA for COVID?

Does taking GABA help with COVID? Find out what’s been shown in our updated answer to the question: Do any supplements help with COVID-19?

Product Review

Multivitamin and Multimineral Supplements Review

Best Multivitamins -- Caution with Gummies

Product Review

Melatonin Supplements Review

Trouble Sleeping? See CL's Tests of Melatonin Supplements and Top Picks.

Melatonin Review 2024

CL Answer

Do any supplements help relieve stress?

Are there actually supplements for stress relief and panic attacks? Learn more about holy basil, fish oil, L-theanine, and ginseng.

Product Review

Black Currant, Borage, Evening Primrose, Flax and Hemp Oil Review

Choose the Best Flaxseed and Other Oils Based on Our Tests.

Omega 3 and 6 Seed Oil Review 2025

News Release

March 09, 2023

L-Theanine Supplements Reviewed by ConsumerLab. Top Pick Chosen.

White Plains, New York, March 9, 2023 —L-theanine supplements are often promoted to reduce stress and improve sleep and cognition.

Product Review

Sexual Enhancer Supplements Review (with Yohimbe, Horny Goat Weed, Arginine)

Choose the Best Sexual Enhancer Supplement. Only 30% of Selected Sexual Enhancement Supplements Pass Quality Tests.

Product Review

Vitamin E Supplements Review

Find the Best Vitamin E Supplement. Tests and Reviews of Popular Vitamin E Supplements & CL's Top Picks.

Vitamin E Supplements, Cream, and Oil Tested by ConsumerLab.com

CL Answer

Do any supplements help reduce menstrual pain or symptoms of premenstrual syndrome (PMS)?

Find out which supplements help reduce premenstrual syndrome (PMS) symptoms, such as mood swings, pain, bloating, irritability and food cravings.

Woman in PJs Holding Stomach from Abdominal Pain

CL Answer

Supplements for Eczema: Some May Help, While Others Don’t

Certain supplements may reduce symptoms of atopic dermatitis (the most common form of eczema), while others don't seem to work. Find out if gamma-linolenic acid, L-histidine, phytoceramides, probiotics, and other supplements may be beneficial.

Young woman with eczema scratching her skin on the inner side of her elbow

CL Answer

Can any supplements be used to reduce inflammation in people sensitive to NSAIDs such as ibuprofen, high-dose aspirin, or naproxen?

Find out if supplements such as turmeric, fish oil, MSM (methylsulfonylmethane), SAMe (S-adenosyl-methionine), boswellia, ginger, white willow bark or arnica may, or may not, be helpful to people sensitive to NSAIDs.

Woman with NSAID-hypersensitivity looking at two supplement containers and wondering if they are safe to take

CL Answer

Hemp Seeds: Health Benefits, Safety, and What To Consider When Picking a Product

Hemp seeds are promoted for heart health, diabetes, boosting testosterone, and other conditions, but do they work? Find out and learn about potential safety concerns.

Whole hemp seeds and hemp hearts in small white bowls

CL Answer

What are the best supplements for depression and anxiety?

Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.

Best Supplements for Depression and Anxiety -- sad young woman sitting on couch, looking toward the window

Clinical Update

6/08/2021

GLA for Inflammation?

Can taking GLA (gamma-linolenic acid) supplements help reduce inflammation? Find out in our answer to the question: Can any supplements be used to reduce inflammation in people sensitive to NSAIDs such as ibuprofen, high-dose aspirin, or naproxen?

Clinical Update

8/04/2023

Black Currant or Caffeine for Hair?

Does black currant seed oil, or its constituent gamma-linolenic acid (GLA), increase hair growth? Find out what research suggests in the GLA section of our ALA and GLA Supplements Review, which includes our Top Pick for black currant seed oil.

Also find out if applying caffeine to the scalp increases hair growth and reduces shedding in our article about supplements and topicals for hair.

Clinical Update

10/10/2024

Light Therapy for Parkinson's?

Does wearing a helmet which delivers red or near infrared light to the head (such as SYMBYX Neuro or VieLight Neuro Gamma) improve symptoms of Parkinson’s disease? Find out what research suggests in our article about light therapies. Also, find out if these helmets help people with mild cognitive impairment.

Recalls & Warnings

July 27, 2012

Prescription and Street Drug Alternatives Found in Male Enhancement, Mood, and Sleep Supplements

On July 10, 2012, the FDA issued a warning letter to Evol Nutrition Associates, Inc. subsequent to a 2011 inspection which found a number of the company's products contained prescription and investigational drugs and were misbranded.

Recalls & Warnings

December 05, 2015

FDA Warns Companies Selling Products Containing Picamilon

On November 30, 2015, the FDA issued warning letters to five supplement companies selling products containing picamilon, which is not a lawful dietary supplement ingredient in the U.S.

News Release

February 23, 2023

Best GABA Supplements Identified by ConsumerLab

White Plains, New York, February 23, 2023 — GABA (gamma-aminobutyric acid) supplements are claimed to have a "calming" effect, and are often promoted to reduce stress and insomnia and improve cognitive performance.

News Release

November 27, 2017

Flaxseed and Other Popular Omega 3 & 6 Oil Supplements Tested, But Not All Brands Pass -- Tests of Black Currant Oil, Borage Oil, Evening Primrose Oil, Flaxseed Oil, and Hemp Oil Supplements

White Plains, New York, November 27, 2017 — Flaxseed oil and other popular seed oil are popular supplements that provide omega-3 and omega-6 fatty acids and may help with inflammatory conditions. But which seed oil supplements are the best? To find out, ConsumerLab.

News Release

May 07, 2014

Flaxseed and Other Popular Seed Oil Supplements Tested by ConsumerLab.com, But Not All Brands Pass -- Flaxseed, Black Currant, Borage and Evening Primrose Oils Reviewed

White Plains, New York, May 7, 2014 — Plant seed oils are popular supplements that provide omega-3 and omega-6 fatty acids, but which products offer the best value and quality? Recent analyses by ConsumerLab.

News Release

June 18, 2012

What is "Natural" Vitamin E? It Depends On the Brand Selling It, Finds ConsumerLab.com -- New Review of Vitamin E Supplements, Oil and Cream, Including Tocopherols and Tocotrienols

White Plains, New York, June 18, 2012 — What is in a "natural" vitamin E supplement, cream, or oil? According to recent tests by independent evaluator, ConsumerLab.com, this depends completely on the brand selling it.

News Release

January 11, 2011

Spoilage and labeling errors found with some omega-3 and -6 supplements; Review of evening primrose, flaxseed, borage, and black currant oil supplements

WHITE PLAINS, NEW YORK — JANUARY 10, 2011 — A new report on the quality of omega-3 and -6 fatty acid supplements made from seed oils was released by ConsumerLab.com today. Only 11 of 17 products selected for testing met quality criteria for freshness and labeling.

News Release

December 10, 2007

ConsumerLab.com finds improvement in quality of omega-3 and -6 supplements — Results for 22 products made from evening primrose, flaxseed, borage and black currant oils

WHITE PLAINS, NEW YORK — DECEMBER 10, 2007 — A new report on the quality of omega-3 and -6 fatty acid supplements made from seed oils was released by ConsumerLab.com today. Two products were slightly low in one fatty acid, but this is an improvement over results from ConsumerLab.

News Release

July 12, 2005

ConsumerLab.com finds some supplements lower in omega-3 and omega-6 fatty acids than claimed — Report available for 23 products made from oils of black currant, borage, evening primrose and flax

WHITE PLAINS, NY — July 12, 2005 — ConsumerLab.com has released its latest report on the quality of supplements made from the seed oils of black currant, borage, evening primrose, and flax.

News Release

August 07, 2002

ConsumerLab.com finds some spoilage and inaccuracy among omega-3 and 6 supplements — List released of evening primrose, flaxseed and other GLA/ALA products that passed testing

WHITE PLAINS, NY — August 7, 2002 — ConsumerLab.com, an independent evaluator of health and nutrition products, released results today of its Product Review of Black Currant, Borage, Evening Primrose, and Flaxseed Oils: Sources of ALA and GLA (Omega-3 and -6 Fatty Acids).

Recalls & Warnings

November 21, 2015

FTC Charges Maker of Supplement for Opiate Addiction with Deceptive Claims

On November 16, 2015, the FTC filed a lawsuit against Sunrise Nutraceuticals, LLC, charging that the company made deceptive claims its product, Elimidrol, can alleviate opiate withdrawal symptoms and increase a user's likelihood of overcoming opiate addiction. 

Recalls & Warnings

August 28, 2013

Maker of Sexual Enhancement Supplement Warned for Manufacturing Violations

On July 11, 2013, the FDA issued a warning letter to Precise Nutrition International Inc.

Recalls & Warnings

March 15, 2013

Maker of Liquid Supplements Warned For Manufacturing Violations and Drug Claims

On January 31, 2013, the FDA issued a warning letter to Liquid Health, Inc.

Recalls & Warnings

September 10, 2012

Maker of Concussion Recovery Supplement Warned For Making Drug Claims

On August 28, 2012, the FDA issued a warning letter to Trinity Sports Group, Inc. after a review of the company's websites found statements about Neuro Impact Concussion Response Formula constituted drug claims not permitted on supplements. 

Recalls & Warnings

October 28, 2015

GNC Accused of Selling Supplements with Unlawful Ingredients

On October 22, 2015, Oregon Attorney General Ellen Rosenblum filed a lawsuit against supplement retailer GNC, alleging that the company sold products that were adulterated with BMPEA and picamilon, which are not lawful dietary supplement ingredients.

Recalls & Warnings

February 18, 2020

Seller of CoQ10, Resveratrol and More Warned for Manufacturing Violations

On February 5, 2020, the FDA issued a warning letter to R-Garden LLC, which found the company's Vitamin O, Gamma-Zyme, L.

Recalls & Warnings

May 14, 2014

Maker of Mood, Smoking Cessation Supplements and More Warned for Violations, Drug Claims

On April 17, 2014, the FDA issued a warning letter to CDJ Holding, Incorporated, d.b.a.

Recalls & Warnings

October 24, 2012

Manufacturer of Green Tea, Vitamin E, Omega-3 and Cranberry Supplements Warned For Manufacturing Violations, Misbranding and Drug Claims

On October 16, 2012, the FDA issued a warning letter to dietary supplement manufacturer Advanced Nutritional Technology Inc.

Recalls & Warnings

November 02, 2012

Manufacturer of Prostate, Inflammation and Cholesterol Supplements Warned For Drug Claims

On October 15, 2012, the FDA issued a warning letter to Ortho Molecular Products, Inc. for making drug claims about the following dietary supplements: Candicid Forte, Inflamma-bLOX, Lipitrol, Mucosagen, Prostatrol Forte, Resvoxitrol, Paracid Forte, VascuPak HTN and Lithium Orotate.