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SAMe Supplements

Most SAMe Supplements Fail Recent Tests

November 21, 2024
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Only 4 of 23 brands of SAMe supplements sold on Amazon were found to contain their listed amounts of SAMe, according to tests by a competing brand. Six products had no SAMe at all. Get the results by brand in the Quality Concerns section of our SAMe Supplements Review, which includes our Top Picks for SAMe.

Misleading SAMe on Amazon

August 08, 2024
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ConsumerLab was informed of another SAMe supplement sold on Amazon with misleading labeling. See the details in the Quality Concerns section of our SAMe Supplements Review. Also see our Top Pick among SAMe supplements.

SAMe Color?

August 01, 2024
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A CL member asked what color SAMe (S-adenosyl-methionine) tablets should be, noting that tablets received from different brands have been different shades of yellow. See our answer in our SAMe Review, which includes our Top Pick for SAMe.

Caution With SAMe

April 15, 2022
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Recent laboratory research suggests caution with the use of SAMe. For details, see the Concerns and Cautions section of our SAMe Supplements Review.

SAMe for Depression?

December 13, 2019
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SAMe (S-adenosyl-methionine) may help some, but not all, people with major depressive disorder, according to a recent study. For details, see the What It Does section of the SAMe Supplements Review. Also see our Top Picks for SAMe.

SAMe for Depression

September 24, 2018
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SAMe (S-adenosyl-methionine) may be helpful in depression, although a recent study suggests that the right dosage can be important. For details, see the What It Does section of the SAMe Supplements Review. (Also see our Top Picks among SAMe supplements).