Reviews and Information for Bupropion (Drug)
Wellbutrin vs. Generic Bupropion
Are there differences between the antidepressant Wellbutrin and generic bupropion? See ConsumerLab.com's independent tests of these drugs, get tips for getting the right drug, and more. If you or a loved one uses generic Wellbutrin, you need to know how products may differ.
Wellbutrin vs. Generic Bupropion ReviewSearch term may appear only in full report available to members. Join now for full access.
Clinical Update
1/17/2023
Antidepressants and Tinnitus?
Find out if the antidepressant bupropion (Wellbutrin) can cause ringing in the ears (tinnitus), and see a list of other medications that may have this effect in our article about tinnitus.
Clinical Update
12/09/2012
Failure of Generic Antidepressant Drug
In October, the FDA withdrew its approval of a generic version of the popular antidepressant drug, Wellbutrin XL. This came 5 years after ConsumerLab.com first reported a potential problem with the drug. This week, more disturbing details emerged about this generic drug and why it was originally approved by the FDA. For more about this, see the Update in the report Wellbutrin vs. Generic Bupropion. More >>
News Release
October 04, 2012
Five Years After ConsumerLab.com Reported a Problem, FDA Agrees Generic Version of Wellbutrin XL Is Not Equivalent and Is Pulled Off Market — Important Lessons about Generics
White Plains, New York — October 4, 2012 [Updated 10/11/12]— Are all generic drugs therapeutically equivalent to their brand name counterparts? Until yesterday, the FDA, and many others, adamantly said they were.
News Release
April 16, 2008
FDA's investigation of generic antidepresssant called inadequate by ConsumerLab.com and The People's Pharmacy
WHITE PLAINS, NEW YORK AND DURHAM, NORTH CAROLINA — APRIL 16, 2008 — After waiting more than six months for results of the FDA's investigation of a generic version of Wellbutrin XL 300 (Budeprion XL 300), ConsumerLab.
News Release
March 17, 2008
As problems surface, Consumerlab.com and the people's pharmacy ask FDA to disclose differences between generic and original drugs
WHITE PLAINS, NEW YORK AND DURHAM, NORTH CAROLINA — MARCH 17, 2008 — An investigation by ConsumerLab.
CL Answer
Do any supplements or lifestyle changes reduce the symptoms of tinnitus? Is it true that some supplements can cause tinnitus?
Learn which supplements can ease tinnitus, including melatonin and pine bark extract. Understand which may actually cause tinnitus.

CL Answer
Do any supplements, foods, or oils help reduce muscle pain, muscle cramps, or nighttime leg cramps?
Find out which supplements, and topical products such as magnesium creams, can help reduce muscle pain, leg cramps, and nighttime leg cramps, and which may worsen muscle cramps. Also, learn about vitamin and mineral deficiencies and common medications that can cause muscle cramps and nocturnal leg cramps.

Clinical Update
10/17/2013
FDA Finds Another Generic Drug Not Equivalent
According to the FDA, a marketed generic version of the antidepressant buproprion hydrochloride XL (300 mg) is not equivalent to the brand name Wellbutrin XL and the product is being removed from the market. One year ago, another generic version of this drug was removed from the market for the same reason. ConsumerLab.com first reported potential problems with these products in 2007 but the FDA was slow to take action. For details, see the updated in the Wellbutrin vs Generic Budeprion Review >>
CL Answer
Do hair loss supplements, such as Viviscal, Hair La Vie, and Nutrafol, or topical essential oils work?
Vitamins and supplements that may help with hair loss and thinning, including saw palmetto, beta-sitosterol, protein, iron, and vitamin D.

News Release
October 12, 2007
ConsumerLab.com finds generic antidepressant behaves differently from original drug. May explain complaints by patients. — Generic drug equality questioned
WHITE PLAINS, NEW YORK AND DURHAM, NORTH CARLOLINA — OCTOBER 12, 2007 — ConsumerLab.
Recalls & Warnings
December 07, 2014
FDA Raises Concerns Over Generic ADHD Drugs
On November 13, 2014, the U.S.
Recalls & Warnings
October 02, 2008
FDA Permits Incorrect Labeling on Generic Wellbutrin XL, But May Require Drug to be Tested
The FDA has acknowledged inconsistencies in the labeling of Budeprion XL, a generic version of the antidepressant Wellbutrin XL, according to an October 2, 2008 article from Dow Jones News service.