Does TA-65 Astragalus Extract Increase Telomere Length and Longevity?

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TA-65 Astragalus Extract for Longevity?

Written by Amy Malec — Medically reviewed and edited by Tod Cooperman, M.D.

Updated April 03, 2025 ⓘ

Answer:

TA-65 (sold by TA Sciences) is a branded Astragalus root extract promoted to lengthen telomeres, the protective "end-caps" on chromosomes that may shorten with age, oxidative stress, and certain disease processes. It is sold as an oral supplement in capsules as well as an ingredient in a face cream, TA-65 for Skin, which is promoted to reduce wrinkles and improve the appearance of prematurely aged skin.

We took a deep dive into the evidence around TA-65 and what it has or has not been shown to do – particularly relating to aging and lifespan. We also investigated potential risks.

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