Do supplements help with Parkinson’s disease treatment or prevention?

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Supplements for Parkinson’s?

Written by Meredith Worthington, Ph.D. — Medically reviewed and edited by Tod Cooperman, M.D.

Updated November 07, 2024 ⓘ

Elderly man with parkinsons holding trembling hand while eating

Answer:

There is no convincing evidence that dietary supplements help delay progression or improve motor impairment in people with Parkinson's disease unless they are deficient in nutrients, although some may help with non-motor symptoms, such as sleep disturbance, depression, and psychoses.

Sign in to learn what has been shown with vitamins D and E, niacin, vitamins B-6 and B-12, coenzyme Q10 (CoQ10), melatonin, creatine, S-adenosyl-L-methionine (SAMe), N-acetyl-cysteine (NAC), valerian, magnesium, curcumin, cannabidiol (CBD), mannitol, PEA (palmitoylethanolamide), and CDP-choline (citicoline), as well as with coffee and the Mediterranean and MIND diets. Also, learn about Mucuna pruriens as a natural source of levodopa (L-dopa) and if labels on supplements are accurate.

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