What are the side effects of ashwagandha supplements?

Answer:

Although ashwagandha supplements (typically taken for anxiety or stress) are generally well-tolerated when taken short-term (weeks to a few months) in typical dosages, mild to moderate side effects such as headache, sleepiness, and stomach upset have been reported in clinical studies (Ramakanth J Ayurveda Integr Med 2016; Chengappa, J Clin Psychiatry 2018). Rarely, liver injury, allergic reactions, and rapid heartbeat have been reported (Philips, Hepatol Commun 2023; Ireland, J R Coll Physicians Edinb 2021; Weber, Am J Gastroenterol 2021; Bjornsson, Abstract in Gastroenterology 2019; Dwivedi, Trop Doct 2011). Ashwagandha can potentially lower blood pressure and blood sugar, and increase thyroid hormone levels (Gannon, J Ayurveda Integr Med 2014; Andallu, Indian J Exp Biol 2000; Panda, J Pharm Pharmacol 1998). Ashwagandha might also stimulate the immune system, which might decrease the effects of immunosuppressant drugs, trigger organ transplant rejection, and induce symptoms of autoimmune diseases (Norris, American College of Physicians Annual Scientific Meeting 2018).

There are no long-term studies on the safety of ashwagandha supplements, and they should not be used by women who are pregnant or nursing.

See the Concerns and Cautions section of the Ashwagandha Supplements Review for more details about the ashwagandha's side effects. The Review includes ConsumerLab's tests and reviews of popular ashwagandha supplements, its Top Pick, and the evidence regarding ashwagandha for anxiety, physical and cognitive performance, and other uses.