What is TUDCA (tauroursodeoxycholic acid)? Does it have any proven health benefits, and is it safe?

Latest Update

TUDCA for Acid Reflux?

Written by Meredith Worthington, Ph.D. — Medically reviewed and edited by Tod Cooperman, M.D.

Updated February 27, 2023 ⓘ

What is Tudca - white capsules poured out of container

Answer:

TUDCA (tauroursodeoxycholic acid) is used a drug (in Europe) and as a supplement in the U.S. primarily for treating certain liver disorders and gallstone issues, although the evidence that it works is limited, and there are potential side effects and drug interactions. TUDCA has also been proposed for treating amyotrophic lateral sclerosis (ALS), insulin resistance, diabetes, fatty liver disease, hepatitis, liver transplant, Alzheimer's disease, Parkinson's disease, multiple sclerosis, ulcerative colitis, and acid or bile reflux. Although it exists in small amounts naturally in the human body, TUDCA in drugs and supplements is made synthetically. Sign in and read the full answer for more information and details, including a comparison of marketed TUDCA supplements.

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