Do Any Supplements Improve Dry Mouth (Xerostomia) or Make It Worse?

Answer:

Xerostomia, a condition commonly referred to as "dry mouth," occurs due to impaired saliva production. Decreased saliva production can result from dehydration, medication use, or medical treatment such as radiotherapy to the head and neck, as well as certain medical conditions including Sjogren's syndrome, HIV/AIDS, hepatitis C, and graft-versus-host disease (a complication that can occur after bone marrow or stem cell transplant) (Plemons, J Am Dent Assoc 2014).

Medications such as pilocarpine (Salagen) and cevimeline hydrochloride (Evoxac) may be prescribed for people with dry mouth to stimulate saliva production. Unfortunately, these medications can cause side effects, including sweating, nausea and stuffy nose, as well as less common effects such as headache and diarrhea (Cohen-Brown, Quintessence Int 2004). Response to these medications can vary depending on the extent of salivary gland damage (Plemons, J Am Dent Assoc 2014).

Due to side effects with prescription medications, people with dry mouth commonly seek over-the-counter products such as oral patches, rinses, lozenges, toothpastes, sprays, gels and gums to help improve symptoms. But do these supplements work?

Sign in as a member to find out which, if any, supplements help improve dry mouth, and if any supplements worsen symptoms. Also, learn which, if any, topical formulations or lifestyle modifications might help reduce symptoms of dry mouth. Supplements and topical products discussed include artificial saliva/salivary stimulants, bacopa, bromelain (an enzyme in pineapple), cannabidiol, ginger, grape seed extract, grape seed oil, papain (an enzyme in papaya), rhodiola, xylitol (including products such as XyliMelts), and zinc carnosine.