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Doctor discussing osteoporosis with older female patient

Answer:

Osteoporosis is a disease in which the density and quality of the bone are reduced, making it weak and brittle. A variety of supplements offer potential benefit, although in limited situations.

Sign in as a member to learn which supplements might help with osteoporosis and which might not, including black currantboron, calcium, collagen, creatine, magnesium, melatonin, probiotics, soy isoflavones, strontium (as strontium ranelate or citrate), vitamin A, vitamin D, and vitamin K, as well as blueberry and the product BoneUp. Also, find out whether diets such as the Mediterranean diet, vegan and vegetarian diets, weight loss diets, acid-producing diets, or a walnut-enriched diet might be helpful for bone health.

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64 Comments

Lidia20118
July 19, 2024

Hello, does anyone have any experience with Ostera by Metagenics?

Janet5131
December 01, 2023

I was diagnosed with osteopenia in 2020. I had been taking a half dose of strontium rotate by Swanson and Life Extension Bone Restore with K2 as well as collagen at the time. Since then, I have taken the full dose of strontium orotate, changed to Life Extension Bone Restore Elite (45 mg of MK4), continued collagen, and began whole body vibration and much increased walking. I just received my DEXA results, and I have remained stable, still in osteopenia but no worse. I am disappointed that I didn't improve, but staying stable at age 72 is okay.

T Allen
March 01, 2024

Congrats!

Christine5124
October 06, 2023

I have been taking Prolia injections every 6 months for my osteoporosis for 3 years now and I now have osteopenia, so my bone mass has improved. I cannot tolerate calcium supplementation in any form (including liquid) because of my severe reflux & chronic constipation. I have not been able to tolerate other treatments for osteoporosis including Reclast infusions. Tried them all except for the oral meds because of my reflux.

MARY5129
November 09, 2023

Thanks for sharing your positive results with Prolia.

Fiona20894
October 15, 2024

Christine, did you have any side effects with Prolia?

Aray
February 27, 2025

My primary care doctor just told me that if I start taking Prolia would need to continue taking it for life. This to me is a significant downside.

Connie22104
February 28, 2025

I will say that I have not had any side effects from Prolia. I have no financial interest in this product. If you try it, I was told to stay on it as scheduled, and if I wanted to go off, I would need to transition to other meds or risk fractures. It is improving my density.

Patricia22181
March 07, 2025

I took Prolia for my osteoporosis. I took 3 doses from the very beginning I did not feel well. I forged ahead because there were no other options. I have mild reflux and could not take the other medication. I decided to go off Prolia. After not receiving my scheduled Prolia I started feeling better, I mean really better. Waited 2 months for the scheduled DEXA scan. Got the results and I was a little worse! Since being off Prolia I have made sure I get enough calcium and am hoping I will not get any worse.

eve5123
October 06, 2023

Comment on "vegan" diet. The problem with studying vegans is you don't know what they're eating. Being a vegan is not necessarily healthy. Most vegans do it for ethical and moral reasons and not for health reasons you can eat french fries Oreos drink liquor and smoke and still be a vegan. Eating a whole food plant-based diet would probably get you enough nutrients. Thank you for a great article.

Catherine19452
May 06, 2024

I agree with you. Plenty of vegetables, fruits, beans, whole grain, nuts & seeds vs. marshmallow fluff & peanut butter on white bread, chips & soda.

Janet20882
October 15, 2024

I agree!!
It seems more research is needed before we can say for sure.

Janette5121
September 24, 2023

I started BoneUp recently due to a doctor recommendation. The suggested serving size of is two capsules and the Magnesium per serving is 166.7 mg. Maybe they have recently changed the formula?

ConsumerLab.com
January 05, 2024

The suggested serving size for BoneUp is 2 capsules three times daily. This would provide a total amount of about 500 mg of magnesium per day, which is above the Tolerable Upper Intake Level from supplements.

Robert5120
September 22, 2023

I led the BoneUp study mentioned here. My goal was just to see if a supplement with calcium + other nutrients + exercise could impact bone metabolism markers. It was supposed to be just a first look. CL correctly states that bone density & strength weren't measured, but that would have been an expensive & lengthy study in this population. I hoped to study the effects of my own formula on stress fractures during Army basic training. However, I never got any funding.

Tina E
July 19, 2024

What a shame!

mary ann5107
June 06, 2023

Recently learned a long with osteoarthritis which shows foraminal stenosis in lower back, some disk issues, I have Osteoporosis, I'm 79. Taking Caltrate for calcium and vit D plus life extension bone restore, cut caffeine, also diet with fruit, veg, dairy, walking, some other exercises that are to help with causing problem for osteo. No added dugs for osteo yet, scared of side effects. Only injection, Dexamatine for back pain. Hope I'm on right track. Thanks

vicki5113
June 13, 2023

I agree with you, I too am afraid of the side effects of the drugs, I am doing the same as you with diet and vitamins.

Dawn5111
September 22, 2023

Vicki and Mary Ann, I urge you to watch this video from NPR: it may alleviate some of your worries.
https://www.npr.org/2009/12/21/121609815/how-a-bone-disease-grew-to-fit-the-prescription

Annette5112
September 24, 2023

Thank you Dan for sharing that informative NPR piece.

Toni5110
October 06, 2023

I add my thanks for pointing us to the NPR article, Dawn. It's an older article (2009), but I doubt things have changed much.

Deborah5115
October 06, 2023

Diagnosed in January with osteoporosis in my lumbar spine (a 3.0 composite score), I started eating prunes daily, saw an acupuncturist, and increased my walking to 2 miles. In July, my composite score had dropped to 2.5, and the bones most affected were the ones that made the most improvements (3.4 to 2.7, etc.) I did not take any medications but added 200 mg of calcium.

Denice R5108
October 20, 2023

how many prunes per day did you eat?

Connie5114
November 03, 2023

I had 5 compression fractures in my back. It has been the most excruciatingly painful experience to date. I am functional but will never be what I was. I show up early every six months for my Prolia injection. (No financial incentive.) Never had a side effect. They would have to be horrific to be worse than the fractures. Weigh your options. Once it happens, there is no do-over.

Idelle21675
January 16, 2025

Thank you Dawn5111 for the NPR article on pharmaceuticals. I was on Fosomax For five years, developed GERD, silent Reflux/LPR., and then Barrett’s esophagus. I am off all drugs for now…. I will continue natural supplements, diet, exercise and hope for the best.

Sylvia Trickler
December 22, 2022

I have had good luck stopping a gerd attack with ginger chews or papaya enzyme chewable tablets.

Kirk5104
January 11, 2023

Melatonin is the best thing my patients have found to improve stomach/esophageal function.

ConsumerLab.com
January 16, 2023

You can find information about melatonin for stomach pain, GERD, and other stomach conditions in the "What It Does" section of our Melatonin Supplements Review https://www.consumerlab.com/reviews/melatonin-supplements/melatonin/#stomach.

Deborah5089
September 17, 2021

In May 2019 I was diagnosed with osteopenia in my hips. I had been taking pantoprazole for GERD for over two years. I believe that pantoprazole was responsible for nutrient deficiencies even though I was taking supplements like calcium, magnesium, and vitamin D. I stopped taking pantoprazole and started taking Jarrow Bone-up, which has made an amazing difference. My hip pain is pretty much gone. I'm sure it's because of Bone-Up, because I tried switching back to my old supplements for a while to finish them off and the pain came back. (All of the above is personal experience. I have no financial interest in any supplements.)

Jill5092
September 18, 2021

This is very interesting to me, as I also have been taking Jarrow Bone-up at a half dose (3 tabs per day) and I also have osteopenia. Have you stayed off the pantoprazole, and have your GERD symptoms gone away? Have you had your osteopenia re-evaluated since May 2019 (i.e. DEXA scan)?

ellen5093
January 10, 2023

Jill & Deborah,
I’m considering adding Jarrow Bone Up for osteoporosis. Can you please update us on your experiences?
Thank you!

Maureen5090
September 19, 2023

I have broken 7 bones and now take Bone-Up. It, and regular walking has improved my bone density. I have no financial interest in Bone-Up.

ConsumerLab.com
September 22, 2023

Thanks for sharing your experience! We've added some information about BoneUp, including results of ConsumerLab tests of BoneUp’s quality, to the following section of our article above: https://www.consumerlab.com/answers/do-any-supplements-help-prevent-or-treat-osteoporosis/osteoporosis/#boneup

Bev5068
May 10, 2019

What about increasing intake of Whole Milk? I prefer food over supplements and have read that the body absorbs better. Buying from a small dairy, brief high heat pasteurization. Not homogenized. A2 protein. Wonderful stuff. Consuming 3 cups daily. Active lifestyle. Mom had severe osteoporosis at age 97. I have not yet had bone density.

ConsumerLab.com
May 10, 2019

Hi Bev - Thank you for sharing this. Milk and dairy products such as yogurt are certainly a good sources of calcium, as are white beans, soybeans, and tofu, as noted in our Calcium Review: https://www.consumerlab.com/reviews/Bone_Supplements-Calcium_with_%20Vitamin_D_K_magnesium/calcium/#food. You may also be interested in our CL Answer about calcium-fortified milks: https://www.consumerlab.com/answers/how-much-calcium-do-you-need-and-what-forms-are-best/calcium/.

Terri5061
September 11, 2018

I am 61 and was diagnosed with Osteoporosis Last January. I have been incorporating a regimen - albeit slowly - based on a book 'The Healthy Bones Nutrituion Plan and Cookbook' by Dr. Laura Kelly and Helen Bryman Kelly. Everything, including supplements, are made from scratch. With my lifestyle, it is very difficult to be consistent and I have been concerned I am not getting enough nutrients, like MK7, D and the other nutrients I need to build bone. Today I ordered AlgaeCal Plus (without the Strontium) for a trial period. My question for you is, I take 40 mg. per day of Pantoprazole for GERD. I have been told that this blocks the absorptions of crucial nutrients and can actually contribute to osteoporosis. Do you have any information on this? I am quite stressed about all of this. Thank you for any help.

ConsumerLab.com
September 13, 2018

Hi Terri - Please see the CL Answer about proton pump inhibitors (such as pantoprazole) and potential interactions with vitamins, minerals and other supplements: https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-proton-pump-inhibitors-ppis/omeprazole-minerals-vitamins/

Patricia5064
February 23, 2022

These prescription meds for GERD and other GI problems are so harmful. Try natural supplements like licorice root. This was very soothing for me and I also added others that help break down food like enzymes.

Kandy
April 07, 2022

My mother took Prescription medications for Gerdes for years. She was ill for a while, lost a lot of weight, and then no longer Had the problems with Gerds. It was amazing!

Marilyn5063
October 15, 2022

I was prescribed the proton pump inhibitors after an upper GI found early Barretts. Did a couple of things. Don’t eat after ~6pm and try to avoid the worst triggers at the evening meal (tomato sauce, onions, greasy food).

Coleen5059
May 24, 2018

I am post-menopausal and was taking calcium supplements until my eye doctor told me I have calcium deposits around my retina, and he recommended that I stop taking calcium supplements. Women are often encouraged to take calcium supplements by their doctor, but rarely do doctors mention situations where one should consider not taking them.

Diane5044
November 10, 2015

I also take a supplement called Ostinol. Do you have any research on Ostinol? As I mentioned previously, with my regimen, my regular DEXA scans show significant bone density increases. I am post-menopausal.

Rita5048
January 06, 2019

Has any one else tried Ostinol? I am interested in hearing any results of using it. I know it is a bit expense, so don't want to buy it if the results are not known.

Linda5053
March 10, 2023

Yes, I take Ostinol and it has worked fantastic for me. I am going by how I feel. The pain, from Osteoporosis, has improved dramatically and I will never stop taking it. I have no financial relationship with Ostinol.

ConsumerLab.com
July 26, 2023

Be aware of the FTC's action against a company for making misleading claims about Ostinol https://www.consumerlab.com/recalls/14336/ftc-sues-two-companies-selling-bone-health-and-joint-pain-supplements/.

Diane5041
November 01, 2015

I take a product called AlgaeCal along with their Strontium Boost. I have taken it for about 3-4 years after discovering that I had osteoporosis in my right hip. I have done about 3-4 Dexa Scans which show a 1-3.5.% increase in bone density in all areas that were scanned each time I did the DEXA. I would be happy to share the scans with you. My formerly osteoporotic hip is now almost in the normal range as is the rest of the areas that were scanned. I think everyone should know about this formulation. I think maybe Dr's Best has a similar formulation, but I am staying with AlgaeCal cause it works.

ConsumerLab.com
November 09, 2015

Hi Diane - Thank you for sharing your experience with AlgaeCal. You can find more information about this product in this CL Answer : https://www.consumerlab.com/answers/how-much-calcium-do-you-need-and-what-forms-are-best/calcium/

Steven5039
September 27, 2015

Vitamin K2 should be specified

ConsumerLab.com
October 01, 2015

Hi Steven - Please follow the link to the Review of Vitamin K Supplements in the answer above for information about both vitamin K1 and K2 (MK-4 and MK-7) for increasing bone density.

Glenda5005
September 27, 2015

I began taking Strontium two years ago, after a bone density test showed some osteo-pina.The doctor wanted me to go on an aggressive form of meds to correct this. I refused, and continued doing all the forms of building bone that you mentioned. The only different thing I did was to add the Strontium. Two years later, much to the doctor surprise, my bone density was greater than the two years before! I followed the directions on the container. So, how much is "too much" Strontium? I am 75 years old. Thanks, G.R.

ConsumerLab.com
October 13, 2015

Hi Glenda - Thank you letting us know about your experience with strontium. We've added information about dosage to the answer above.

Lani5008
October 30, 2015

Hi Glenda,

I am a bone densitometrist. Strontium falsely increases bone density. We do not know how much exactly in any given person. The other issue is that someone your age will typically increase bone density in the spine due to arthritic changes. Osteopenia is not considered a diagnosis necessarily. If you have had fractures that were low-trauma that is another matter. The main question is will strontium citrate reduce fracture risk? Many things can increase bone density yet increase fracture. A good example of this is high doses of flouride - increases bone density, but the bone quality is poor.
Sincerely,
Lani Simpson, DC, CCD
Author: Dr. Lani's No-Nonsense Bone Health Guide

Robin5030
May 14, 2017

Just saw this post today. Thanks so much for this important information!! I wish CL would highlight it. Not all primary docs are aware of this issue.

Anita5014
November 16, 2017

Actually, although strontium does give a false reading on DXA scans, these are crude forms of imagery. Different imaging, and in fact biopsies, show that bone structure actually improves with strontium treatment. There are many studies in rodents but here are biopsy results of a human patient.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023638

I myself take strontium citrate and other supplements, following the Canadian micronutrient protocol created by Dr. Stephen Genuis. https://www.hindawi.com/journals/jeph/2012/354151/

I rebuilt my bone mass, though it is only measured by DXA.

Before I began this protocol, I asked my (now) late father-in-law, who was the longtime pharmacology department chair at a large eastern medical school, whether it would be stupid to take strontium citrate, and he told me that a colleague who suffered from a rare early-onset osteoporosis was treated with strontium salts at the Mayo Clinic in the 1960s. His fractures ceased and he took strontium the rest of his life, another thirty or so years.

ellen5015
May 08, 2019

Hi Anita,
I have just come across your post. I’m considering adding strontium to my regime. Are you still taking it? Can you share the brand you use?
Thanks so much!

Anita5017
September 25, 2019

Hi Ellen, I'm sorry, I just saw your question. Actually my life has gotten complicated the last couple of years and I have been struggling even to consume enough calcium every day, and you don't want to take strontium unless you have sufficient calcium--the idea is that you take strontium to promote bone regrowth, not to replace calcium in the bone matrix. So, when I was taking strontium I took Doctor's Best but that is no longer being made. I have since bought strontium from VitaCost, but I was thinking next time I purchased strontium I might get it from Algaecal. (Per Consumerlab's request, I state that I have no financial in these or similar products.)

Here are links to columns by the late Sara DeHart, a professor of nursing, that you might find useful:

http://www.intrepidreport.com/archives/2608
http://www.intrepidreport.com/archives/2612
http://www.intrepidreport.com/archives/1246

There are caveats to taking strontium, the primary one being that if you have had or have a cancer that metastasizes to bone, you do NOT want to promote bone growth. Also, the drug form of strontium, strontium ranelate, has been associated with a slightly increased risk of blood clots, so if you have had phlebitis you might not want to take strontium either. I do not take it when I fly or drive long distances for this reason. There are other issues associated with strontium ranelate that have not been reported with strontium citrate, but as strontium citrate cannot be patented, we are unlikely to ever see any studies undertaken.

Jani5018
June 01, 2020

I have read tht one must be extremely careful taking Strontium if their kdneys are not healthy. Check your Glumeral Function.

Jeanne5022
June 05, 2019

I know this is an old post, but felt it important to mention that biophosphonates, like Fosomax etc have also been criticized for increasing bone density, but creating poor quality bone.

ellen5023
July 21, 2019

Yes, I’ve read & heard about this.

Marcella5033
June 22, 2021

I have metastatic breast cancer which has spread to bones. Don't understand te comments above of not wanting to increase bone mass. I have bee taking calcium supplents as well as injection of Xgeva e ery 3 months as presctibed by my oncologist. Very confused.

ellen5006
June 30, 2021

Thank you, Anita, for the useful links.

Suzanne5036
June 30, 2021

Also for those reading this, I have had decreased bone density since my mid-thirties due to a health condition but found the Bone Booster formula by VitaCost that's based off of the Bone-Up formula but tweaked and found my body LOVES it. I have increased my bone density (measured by DXA) due to it as my exercise regimen has remained the same and my diet is solid. I'll def. consider trying this as well. I have zero affiliation professionally or financially to the products mentioned.

ellen5034
July 02, 2021

Suzanne, that is great news about your success with a supplement!!
I will look into this. Thank you so much for sharing your positive experience.

Anita5037
September 10, 2021

Marcella22792, I am very sorry to hear about your cancer. Now that you're under treatment your oncologist can balance your bone density issues with cancer suppression.

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