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Our Members Asked:
Do any supplements help prevent or treat a cold?

Answer:
Certain supplements can reduce the chance of getting a cold, while others may help reduce the severity of a cold or relieve cold symptoms. Other supplements don't seem to be beneficial for colds, but they may help prevent or treat other types of respiratory infections or inflammation. On the other hand, some supplements that are promoted for preventing or treating colds may not be beneficial.
Sign in as a ConsumerLab member to learn which supplements may help and which don’t. Supplements discussed include andrographis, astragalus, beta-glucan, bovine colostrum, bromelain, echinacea, elderberry, fish oil, garlic, glutathione, ginseng, honey, melatonin, NAC (N-acetyl-cysteine), olive leaf extract, pea (palmitoylethanolamide), postbiotics, prebiotics, probiotics, propolis, vitamins C and D, and zinc, as well as the branded products Emergen-C, Wellness Formula, and Oscillococcinum.
In addition the results of its expert testing, ConsumerLab uses only high-quality, evidence based, information sources. These sources include peer-reviewed studies and information from agencies such as the FDA and USDA, and the National Academy of Medicine. On evolving topics, studies from pre-print journals may be sourced. All of our content is reviewed by medical doctors and doctoral-level experts in pharmacology, toxicology, and chemistry. We continually update and medically review our information to keep our content trustworthy, accurate, and reliable. The following sources are referenced in this article:
- Abuelgasim, BMJ Evid Based Med 2020
- Auinger, Eur J Nutr 2013
- Esposito, Phytomedicine 2021
- Feldman, J Appl Res 2009
- Josling, Adv Ther 2001
- Kumazawa, Food Chem 2004
- Magnavacca, Med Res Rev 2021
- Pu, Heliyon 2024
- Somerville, Nutrients 2019
- Talbott, J Sports Sci and Med 2009
- Vielma, Acta Trop 2014
- Weissman, Dig Dis Sci 2019
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45 Comments
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Latest Research Updates (Clinical Updates)
Propolis for Colds?
December 12, 2024
Propolis for Colds?
December 12, 2024
Wellness Formula for Colds?
October 18, 2024
The product Wellness Formula by Source Naturals is said to support the immune system to help people avoid sick days. Is there evidence of that? Find out in our article about supplements for colds.
Also see: Do any supplements help for flu?
Vitamin D to Prevent Winter Colds & Flu?
September 26, 2024
Does taking vitamin D help prevent respiratory infections during winter? Find out what a recent study showed in the Respiratory infections, colds and influenza section of our Vitamin D Supplements Review, which includes our Top Picks.
EpiCor for Colds and Flu?
July 08, 2024
Also see: Do any supplements help prevent or treat a cold?
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The "Updated" date indicates when new information was most recently added to this article. In the full article, the newest information is highlighted in yellow.
J21439
December 15, 2024I used to get colds and 'flu regularly, and frequently suffered from sinus issues. Since taking Propolis capsules for 20 years, I have never had anymore.
Reply to this post…
Joann20904
October 18, 2024Wellness is my go to if I think I am coming down with the flu.(3-3X a day) Wellness worked for Covid-19.. Took those 6 pills a few days and felt better, than I took NAC and really felt better.
Colds I have a warm glass of Emergen-C
Reply to this post…
Cory F
October 18, 2024I have taken Wellness Formula by Source Naturals for the purpose of cold abortion and treatment (i.e., I only start taking it at the first sign of symptoms and then continuously through any cold) for over 14 years. I'm always hesitant to offer recommendations, but I can say that a strong majority of the time I feel initial cold symptoms or have been exposed to a cold (like from my roommates having it) and take Wellness Formula, I end up not experiencing a cold at all, so my experience has been quite positive. If you decide to try it, I recommend the tablets instead of the capsules since only half as many are required (3 vs. 6), and with the capsules I've sometimes coughed up the "dust" inside the capsules later on, which is quite unpleasant. However, be absolutely sure you have a chaser ready, because those tablets are NASTY tasting (and smelling)!
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Sean20005
July 13, 2024Cold-eeze has worked wonders for me. I am extremely susceptible to colds. I have tried zycam but found it to be significantly less effective for myself. I am not affiliated with anything above.
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MizzF
December 07, 2021Reading the updates to an older article. This is why I became a member - to not waste time and money on supposed cures, but I'm also open minded to try new things and want good health! Lots of comments about a product appearing to work for an individual who then feels it is no longer necessary to get a flu shot. As someone who was hospitalized multiple times for respiratory infections as a child, I have been getting my flu shot pretty regularly for about 15 to 20 years since I became an adult and got easy access through my employer. Just because you didn't get sick doesn't mean you didn't spread the flu. These are pre-pandemic articles I liked to share about the benefits of the flu vaccine. If I can help kids avoid the hospital like I did as a kid, then I'm all for it! I'm all for taking some epicor, zinc, and/or quercetin to integrate all of my options for good health.
https://www.nbcnews.com/health/kids-health/mandatory-flu-shots-kept-small-kids-out-hospitals-n46186
https://www.cidrap.umn.edu/news-perspective/2014/03/uk-flu-study-many-are-infected-few-are-sick
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Steve4985
February 27, 2019Beta glucan in some studies is maybe the ultimate immune system support item. I have had no major sickness other than digestive issues in 3 years of using it. I don't get flu shots anymore. I visit a old person's retirement home environment a couple of times a week and work in a construction type environment in and outside, sometimes eat with dirty hands. I am in no means saying Beta Glucan can upset my stomach. Bad food does that.
Isabel4987
September 02, 2020I read yesterday that Dr. Fauci and others are skeptical of claims that a supplement could help boost the immune system because1) most people’s immune systems probably don’t need to be boosted and 2) sending it into overdrive could be dangerous. I suppose they mean a cytokine storm? which I've read (sorry, I can't remember where) could be one explanation for COVID. I'd be very interested to hear your views!
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Gail4984
December 10, 2017My go to for signs of a cold is Grapefruit Seed Extract. IMHO, Taken 3 times a day at first sign and until symptoms decline has kept my 80 year old body and my college going granddaughter cold free for the 2 years I have known about it.
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Isabel4983
December 03, 2017To defeat a cold I use a product called Viragon from Baseline Nutritionals. It has never failed me when taken at the very first symptom - even when I'm not sure it's a symptom yet. Doesn't do a thing if taken too late.
The downsides are 1) it's not cheap and 2) it tastes awful. Well it would - it contains things like horseradish. Well worth it though, in my opinion.
I have no financial interest in this or a competing product.
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Linda4980
December 03, 2017Missing from this list is elderberry extract. Taken at the first minor sign of a cold it can prevent the cold. Taken after it starts it can reduce the length and severity. This is from my own experience, that of the person who recommended it, and the experience of every person to whom I have recommended it.
Hi Linda - Thank you for sharing your experience with this. We've added information about elderberry extract in the answer above.
Julie Ann
October 27, 2019I stopped taking the flu shot, tired of spending every winter and some summers with the flu even after 2 flu shots and started taking Nature's Way Elderberry every day for the past 27 years. I had read about it in a medical journal. I have not had the flu in 27 years.
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Dayle4978
December 03, 2017I have had extraordinarily good experience over many many years using tincture (liquid pure) Echinacea for preventing colds from settling in and taking over. My fave brand is Herb Pharm (usually Super Echinacea), but I have used others. This my experience, and also works for my husband. This works best when 1. I catch it early, at first notice of symptoms like scratchy throat, a wet-ish sneeze, a bit of a drip, and 2. I use 2 or 3 full droppers-full (depending on how incipient and strong the symptoms) in a little water up to several times a day for up to a couple of days. Often symptoms retreat within a day.
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David4974
December 03, 2017While there is "little quality evidence to support these remedies" [homeopathic remedies, that is], there is now clear evidence that homeopathic preparations are no better than placebo.
T Allen
October 28, 2019Even if homeopathic is "only" the placebo effect (it isn't because it works on animals too) the "placebo effect" is actually powerful medicine. It's just not medicine you can make money off of so Capitalists try and deny it. All healers worldwide, except Western medicine, understand that we are energetic beings and we are affected by things that influence our energy. Google "energy medicine the scientific basis" if you want to see the science.
It is true that placebos can appear to have an effect. However, it is the role of good clinical trials to identify remedies that do more than a placebo -- which is what we look for at ConsumerLab when we evaluate the literature around a product. Of course, something that has a real effect typically has side-effects, about which we also report, and these need to be weighed against the possible benefits.
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Vinod4969
January 05, 2016My readings show that beta glucan (1,3 and 1,6) has properties that helps with many infections. I have found it useful. Also looked at any possible negative effects of beta gluten and found none. I would love to have CL comment.
Hi Vinod - We've now added information about beta glucan to the answer above.
Reply to this post…
Steve4967
January 04, 2016Please address the use of mushrooms for their ability to boost immunity, like Reishi mushrooms and the others included in supplements such as Host Defense by MyCommunity. They have outstanding reviews on Amazon, and when I had a review of SpectraCell Lab results, I was told I should take Host Defense to boost my immunity.
Hi Steve - We've added a CL Answer about reishi mushroom supplements here: https://www.consumerlab.com/answers/do-reishi-mushroom-supplements-boost-the-immune-system/reishi-mushroom/
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Kate4959
January 03, 2016I have not seen any comments about EPICOR ~ the supplement derived from yeast ~ which my family and I have taken daily during the winter months for a few years to prevent colds ~ it works !!
Hi Kate - We've now added a CL Answer about EpiCor here: https://www.consumerlab.com/answers/does-epicor-really-work/epicor/
JARKKO4960
December 02, 2017https://www.consumerlab.com/answers/does-epicor-really-work/epicor/
Larger, INDEPENDENT studies are needed to confirm these benefits as well as the long-term safety of Epicor.
So I will not buy now 2017.12
Jenny4961
October 27, 2019I had a worsening of MS after taking Epicor. A naturopath wasn’t convinced it was caused by Epicor and recommended I try it again. I did, and again had a worsening of MS. So, it certainly seemed to boost my immune system. Caveat emptor if one has autoimmune illnesses worsened by such an effect, or a genetic tendency towards.
James D4964
December 10, 2017I have had dramatic result using Epicor. Whereas before using I had several colds a year I have had none since I started using it about five years ago. The same has been true for other members of my family.
JARKKO4966
February 21, 2019A new product from contains Epicor: Life Extension Florassist Nasal. It is expensive, but the main reason for high cost is probably the other ingredient it contains: Lactobacillus acidophilus L-92.
Epicor is from USA and L-92 is from Japan. L-92 is probably expensive even if you travel to Japan and buy it there.
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Stephanie4956
October 04, 2015I have been using ELDERBERRY STANDARIZED for decades. In Germany it is taken throughout flu season. Echinacea when taken over 10 days lowers immune system. Too much zinc has toxic effects. STANDARDIZED ELDERBERRY, has been my go to for decades. When I fly I take one prior to flying and then another after landing. Now, I no longer get airplane flus or colds. Just be sure it is standardized otherwise who knows what you are getting. Haven't had the flu in years. No flu vaccine for me. If you do get sick take Elderberry ASAP and your flu or cold days and severity will be greatly reduced.
Good life and good health to all.
Sobe
MARCIA4957
October 19, 2019Looks like there are many research articles on the efficacy of elderberry. Hope Consumer Labs will give us an idea on which ones are best as far as having good manufacturing practices and price.
Hi Marcia -- We will be testing elderberry supplements this year, so be sure to check your newsletter, where the results will be announced when the results are published.
Reply to this post…
Robert4954
October 01, 2015My son had purchased a zinc solution for use in detecting zinc deficiency. Feeling a cold coming on and being aware of Zicam, a zinc nasal spray product for dealing with colds, I decided to try snorting some of the solution up each nostril. I feel this worked in one application to knock out the cold virus. I have used it two or three times now. I believe Zicam is no longer sold in this country as there were reports that it permanently damaged the sense of smell in some users. The zinc solution I have is zinc sulfate heptahydrate in purified water, whereas Zicam contains zinc acetate and zinc gluconate and other things.
Hi Robert - Based on the concerns with zinc given nasally, this approach seems risky. In addition, zinc's benefits have only been shown when used every few hours, not as a single application.
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Carol4948
September 28, 2015Umcka Original Drops work great for me. It is best to start before the cold symptoms really take hold. If my throat gets scratchy or sore, or I'm sneezing more than I should... you know that time in process when you naively hope it won't get worse but then it does. Start then.
I will also start it when I know I've been exposed, such as when my partner has gotten sick, or when I've been in a car with someone in the contagious phase. Then I don't get sick at all.
It seems to keep the symptoms from getting worse while my immune system knocks out the virus. I take it up to 5 times a day for a few days, then taper off over a couple of weeks. I've avoided having a full blown cold for years now.
They also have a Cold & Flu version, but I haven't tested that.
Carolyn4953
October 02, 2015Agreed! I have been using it for over 10 years and always have a bottle on hand! It almost always works to prevent, unless the cold has gotten too far along. And I have suggested this product to several friends and family, whoever has tried it, has found it to work as well. It's a Swedish herbal, I get the "original" drops, add it to a bit of water. It has a pleasant, light taste. I understand it boosts the immune system temporarily. Not useful over an extended period.
Sandra4950
December 03, 2017I use the syrup and day/night powder at the first sign of cold and it seems to lessen severity and shorten duration. I like that it has quite a bit of research showing efficacy.
Jada
December 03, 2017I too am a big fan of UMCKA. the active ingredient Pelargonium is an African herb used for bronchitis. But UMCKA ColdCare knocks out my cold fast. I use the extra relief mint-menthol formula.
Kim4949
December 11, 2017I've been using Umcka for 10 years and have told dozens of people about it. I understand that it as approved by the German Commission E, for what that is worth.
I also rely on Quercetin which usually comes with Bromelain.
richard4952
December 17, 2023I have read many good comments on this. I was going to purchase it but then I read one should NOT take it if they have multiple sclerosis. My wife has it so I did not try it.
Susan21404
December 13, 2024Yes I also have used umcka for years. I find it is highly effective at warding off respiratory infections , but not so good if the infection is already established …
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Dennis4945
September 28, 2015There are two protocols I have used over the past 5 years to prevent colds and nip them in the bud when the symptoms first surface. Before i disclose the protocols let me add that prior to 5 years ago a routinely had 4-6 upper respiratory events a year with a severe episode of bronchitis once ever 2-3 years. The first protocol is started at the first signs of a viral infection. It involves following the anti-viral program spelled out in the Life extension website at LEF.org. The ingredients include supplements having antiviral properties. These include pure garlic, Cimetidine (from Tagamet), DHEA, Lactoferrin, Zinc Loenges, Aged Garlic Extract (Kyolic brand) and Melatonin. For the last two years I have not used this protocol as I have had no serious cold symptoms. Two years ago I started taking Glutathione (GSH), the Setria formulation, 1000 mg/day. The friend who put me onto GSH claims to have not had a serious cold in 15 years.
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Judy4944
September 28, 2015At the first sign of a cold, andrographis capsules, 3 x day for a few days and the cold does not develop and symptoms are gone.
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X-tine4943
September 27, 2015Does the herb "andrographis" have an effect on colds?
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terrence4942
September 27, 2015Try cold fx it really helps! Personal experience.
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Carol4941
September 27, 2015I find the combination of Yin Chiao and Oscillococcinum to be infallible. HOWEVER the Oscillo is only effective if taken at that first moment when you think you "might" be getting a cold. Take it then follow with Yin Chiao for three days, whether or not you feel better, which you most likely will. I also use zinc lozenges. Remember with the Oscillo to follow the instructions for all homeopathic remedies -- no peppermint, alcohol, coffee, clean mouth, etc.
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James-Henry4938
September 27, 2015Can any of this be generalized to influenza? If not, could you do a follow-up article about supplements and the flu?
Thank you for your question, James. Please see our separate CL Answer about supplements for flu: https://www.consumerlab.com/answers/do-any-supplements-help-for-flu/supplements-for-flu/
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