Answer:
Supplementing daily with vitamin B12 (100 mcg to 500 mcg) and, possibly, folic acid (400 mcg), may help slow age-related declines in memory and cognition if you're not already getting enough vitamin B12 from your diet or not able to extract it from foods -- a common problem in older people.
The benefit may be enhanced when you're also getting a good amount of omega-3 fatty acids (DHA and EPA), such as from oily fish. Getting the recommended daily allowance of B6 (about 1.7 mg), which is easily obtained from foods, is also important.
For more details see the "Memory, Cognition, and Alzheimer's Disease" section of the B Vitamins Review, which includes our Top Picks among products we have tested. The Review also includes information about good food sources of vitamins B12 and B6.
To increase omega-3 fatty acid intake from food (while minimizing mercury exposure), see the Canned Tuna and Canned Salmon Review as well as the Fish Oil Supplements Review.
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